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A ‘Game Changer’ For Organ Transplants: Blood Type of Donor Kidneys Altered in Breakthrough Research_我的网站

一 | Breakthrough new research could significantly increase supply of organs for people with rarer blood types waiting for a transplant, reported The Guardian.,A team of scientists from the University of Cambridge have successfully altered the blood type of three donor kidneys. By flushing blood infused with a special enzyme through a human kidney the scientists removed the blood type markers lining the blood vessels of the organ.,The procedure required using a device that is connected with a donor’s kidney to pass oxygenated blood through it - a normothermic perfusion machine. As a result, the organ was converted to type O, considered the universal donor.,Blood Group Compatible,As the blood type of a donor must be compatible with the recipient’s, the new development could increase the supply of kidneys available for transplant.,A kidney from someone with blood type A cannot be transplanted to someone with blood type B, or visa versa. In such a case, the receiving body’s immune system would reject the new organ, interpreting the different blood type as foreign.,So changing the blood type to the universal O would mean the donor organ could be used for people with any blood type.,“Our confidence was really boosted after we applied the enzyme to a piece of human kidney tissue and saw very quickly that the antigens were removed. After this, we knew that the process is feasible, and we just had to scale up the project to apply the enzyme to full-size human kidneys,” Serena MacMillan, a PhD student at the University of Cambridge, said.,Scientists involved in the research, funded by charity Kidney Research UK and due to be published in the British Journal of Surgery, clarified that the outcome might have particular implications for minority ethnic groups.,Science & TechGood News for ABs: Scientists Can Now Change People's Blood Type21 February, 16:34 GMT,Some blood groups such as O Rh positive and B Rh positive are more prevalent among black, Asian and minority ethnic communities. To complicate matters further, some rare blood types are only found within the black, Asian and minority ethnic communities,This typically places them at a disadvantage, as they struggle to find a match. With low donation rates from these populations, stressed the researchers, sometimes such patients wait for as long as over a year for a compatible donor. They cited figures from 2020-21 showing that just over 9% of total organ donations in the UK came from black and minority ethnic donors. On the other hand, black and minority ethnic patients make up 33% of the kidney transplant waiting list.,“It’s very exciting to think about how this could potentially impact so many lives,” added Serena MacMillan.,The “potentially gamechanging” research was applauded by Dr Aisling McMahon, the executive director of research at Kidney Research UK.,The scientists will now test the reintroduction of other blood types and observe how the novel approach in clinical settings.。
ESPN记者Don Van Natta Jr.、Baxter Holmes和Ramona Shelburne联合撰文报道,据三位了解NBA与快船近期讨论情况的人士透露,NBA目前未发现有证据证明快船老板鲍尔默通过球队赞助商向科怀·伦纳德输送资金以规避工资帽。相反,两位消息人士称,NBA的关注焦点在于球队将伦纳德介绍给赞助商的行为是否构成违反联盟禁止规避工资帽的规定。
针对ESPN的报道,快船官方发表声明,具体如下:
快船曾将包括科怀·伦纳德在内的球员引荐给我们有业务往来的公司。

二 | 在球队和球队合作伙伴之间进行引荐,既是NBA球队的常规做法,也是球员及其代表普遍提出的要求。此后,科怀及其代表自行处理了谈判事宜。

三 | 快船并未参与谈判或决定科怀代言协议的条款,也未确定他的报酬金额。
我们的商业关系基于其自身价值而建立。我们选择赞助商、供应商及其他商业伙伴,均是依据正常的商业考量,包括他们所提供的价值、产品和服务质量,以及满足我们业务需求的能力。

四 | 我们并未向任何供应商超额付款,也未向任何赞助商、供应商或商业伙伴提供折扣或其他优惠条件,以变相向科怀输送资金。

五 |
球员与球队的某家商业伙伴存在代言关系,这一事实本身并不构成规避工资帽的证据。

六 |
经过近一年的审查,核心事实依然真实且未变:快船并没向科怀·伦纳德输送资金,没安排他人代表我们向其支付报酬,也未以其他方式在其NBA合同之外向其提供未公开的补偿。

七 |
相关内容:
名记:NBA目前未发现有证据证明鲍尔默通过赞助商向小卡输送资金
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